{"id":779,"date":"2009-06-14T20:00:00","date_gmt":"2009-06-14T11:00:00","guid":{"rendered":"http:\/\/testwww.seibutsushi.net\/blog\/2009\/06\/731.html"},"modified":"2009-06-14T20:00:00","modified_gmt":"2009-06-14T11:00:00","slug":"y%e6%9f%93%e8%89%b2%e4%bd%93%e3%81%ae%e4%b8%8d%e6%80%9d%e8%ad%b0%ef%bc%9a%e5%a4%89%e7%95%b0%e8%93%84%e7%a9%8d%e4%bd%93%e3%81%8b%ef%bc%9f%e5%a4%89%e7%95%b0%e4%bf%83%e9%80%b2%e4%bd%93%e3%81%8b%ef%bc%9f","status":"publish","type":"post","link":"http:\/\/www.seibutsushi.net\/blog\/2009\/06\/779.html","title":{"rendered":"Y\u67d3\u8272\u4f53\u306e\u4e0d\u601d\u8b70\uff1a\u5909\u7570\u84c4\u7a4d\u4f53\u304b\uff1f\u5909\u7570\u4fc3\u9032\u4f53\u304b\uff1f"},"content":{"rendered":"<p><img loading=\"lazy\" alt=\"Y%E6%9F%93%E8%89%B2%E4%BD%93.gif\" src=\"\/blog\/wp-content\/uploads\/Y%E6%9F%93%E8%89%B2%E4%BD%93.gif\" width=\"271\" height=\"354\" \/><br \/>\n\u3053\u306e\u753b\u50cf\u306f<a href=\"http:\/\/www.ramsdale.org\/dna13.htm\">\u3053\u3061\u3089<\/a>\u304b\u3089\u304a\u501f\u308a\u3057\u307e\u3057\u305f\u3002<br \/>\n<a href=\"http:\/\/www.biological-j.net\/blog\/2008\/02\/000396.html\">\u6027\u67d3\u8272\u4f53\u306f\u5909\u7570\u306e\u6a21\u7d22\u6a5f\u69cb\uff5e\u7b2c87\u56de\u306a\u3093\u3067\u3084\u5287\u5834\u3088\u308a\uff5e<\/a>\u306e\u4e2d\u306b\u3001<span style=\"color:#6666ff;\">\u300c\u907a\u4f1d\u5b50\u5909\u7570\u306f\uff39\u67d3\u8272\u4f53\u306b\u84c4\u7a4d\u300d<\/span>\u3068\u3044\u3046\u8aac\u660e\u304c\u3042\u308a\u3001\u305d\u306e\u4ed5\u7d44\u307f\u3092\u8abf\u3079\u3066\u3044\u305f\u3068\u3053\u308d\u3001Y\u67d3\u8272\u4f53\u304c\u5909\u7570\u3092\u84c4\u7a4d\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u308b\u3068\u3001\u3064\u3058\u3064\u307e\u306e\u5408\u308f\u306a\u3044\u3053\u3068\u304c\u898b\u3064\u304b\u3063\u3066\u6765\u307e\u3057\u305f\u3002<br \/>\n<span style=\"color:#6666ff;\">Y\u67d3\u8272\u4f53\u306f\u5909\u7570\u3092\u4fc3\u9032\u3059\u308b\u5f79\u5272\u3092\u62c5\u3063\u3066\u3044\u308b<\/span>\u3001\u305d\u3057\u3066\u3001\u5909\u7570\u306e\u84c4\u7a4d\u306f\u4ed6\u306e\u907a\u4f1d\u5b50\u304c\u62c5\u3063\u3066\u3044\u308b\u3068\u8003\u3048\u308b\u65b9\u304c\u3001\u4e0a\u624b\u304f\u8aac\u660e\u3067\u304d\u305d\u3046\u3067\u3059\u3002<br \/>\n\u8208\u5473\u306e\u3042\u308b\u65b9\u306f\u5fdc\u63f4\u3082\u304a\u9858\u3044\u3057\u307e\u3059\u3002<br \/>\n<a href=\"http:\/\/blog.with2.net\/link.php?548466\" target=\"_blank\"><img alt=\"\u30d6\u30ed\u30b0\u30e9\u30f3\u30ad\u30f3\u30b0\u30fb\u4eba\u6c17\u30d6\u30ed\u30b0\u30e9\u30f3\u30ad\u30f3\u30b0\u3078\" src=\"\/blog\/wp-content\/uploads\/banner_04.gif\" \/><\/a> <a href=\"http:\/\/science.blogmura.com\/in\/073660.html\" target=\"_blank\"><img loading=\"lazy\" height=\"15\" alt=\"\u306b\u307b\u3093\u30d6\u30ed\u30b0\u6751 \u79d1\u5b66\u30d6\u30ed\u30b0\u3078\" src=\"http:\/\/science.blogmura.com\/img\/science80_15.gif\" width=\"80\" \/><\/a> <a href=\"http:\/\/blogranking.fc2.com\/in.php?id=92199\" target=\"_blank\"><img src=\"\/blog\/wp-content\/uploads\/pic\/e_03.gif\" \/><\/a><\/p>\n<p><!--more--><br \/>\n<br \/>\n<span style=\"font-size:130%;\"><span style=\"color:#009933;\">\u25cf\u76f8\u540c\u67d3\u8272\u4f53\u304c\u3042\u3063\u3066\u3082X\u67d3\u8272\u4f53\u306f\u4fee\u5fa9\u3055\u308c\u3066\u3044\u306a\u3044<\/span><\/span><br \/>\n<br \/>\n<a href=\"http:\/\/www.biological-j.net\/blog\/2008\/02\/000396.html\">\u5148\u307b\u3069\u7d39\u4ecb\u3057\u305f\u30d6\u30ed\u30b0\u8a18\u4e8b<\/a>\u306b\u306f\u3001X\u67d3\u8272\u4f53\u306f\u76f8\u540c\u67d3\u8272\u4f53\u304c\u3042\u308b\u305f\u3081\u306b\u7a81\u7136\u5909\u7570\u304c\u3042\u3063\u3066\u3082\u4fee\u5fa9\u3057\u5909\u7570\u3092\u84c4\u7a4d\u3057\u306a\u3044\u306e\u306b\u5bfe\u3057\u3001Y\u67d3\u8272\u4f53\u306f\u76f8\u540c\u67d3\u8272\u4f53\u304c\u306a\u3044\u305f\u3081\u5909\u7570\u304c\u4fee\u5fa9\u3055\u308c\u305a\u306b\u5909\u7570\u3092\u84c4\u7a4d\u3059\u308b\u3001\u3068\u3042\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u8a73\u3057\u304f\u8abf\u3079\u3066\u307f\u308b\u3068X\u67d3\u8272\u4f53\u3082\u76f8\u540c\u67d3\u8272\u4f53\u304c\u3042\u308b\u304b\u3089\u3068\u3044\u3063\u3066\u3001\u4fee\u5fa9\u306f\u884c\u306a\u308f\u308c\u3066\u3044\u306a\u3044\u3088\u3046\u3067\u3059\u3002\u5177\u4f53\u7684\u306a\u4e8b\u4f8b\u3068\u3057\u3066\u3001\u8840\u53cb\u75c5\u306e\u4e8b\u4f8b\u3092\u6319\u3052\u3066\u307f\u307e\u3057\u3087\u3046\u3002<br \/>\n<br \/>\n<img loading=\"lazy\" alt=\"%E8%A1%80%E5%8F%8B%E7%97%85.gif\" src=\"\/blog\/wp-content\/uploads\/%E8%A1%80%E5%8F%8B%E7%97%85.gif\" width=\"259\" height=\"254\" \/><br \/>\n\u3053\u306e\u753b\u50cf\u306f<a href=\"http:\/\/www.bayer.co.jp\/hemophilia\/02\/1_3.html\">\u3053\u3061\u3089<\/a>\u304b\u3089\u304a\u501f\u308a\u3057\u307e\u3057\u305f<br \/>\n<br \/>\n\u8840\u53cb\u75c5\u306e\u3088\u3046\u306a\u907a\u4f1d\u75c5\u306f\u3001\u7537\u6027\u306b\u591a\u304f\u767a\u751f\u3057\u307e\u3059\u304c\u3001\u305d\u306e\u907a\u4f1d\u5b50\u7570\u5e38\u306fX\u67d3\u8272\u4f53\u4e0a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u539f\u56e0\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u6b63\u5e38\u306a\u7236\u89aa\u3068\u8840\u53cb\u75c5\u4fdd\u56e0\u8005\u306e\u6bcd\u89aa\u304b\u3089\u751f\u307e\u308c\u305f\u5b50\u4f9b\u306f\u3001\u7537\u306e\u5b50\u306f50\uff05\u306e\u78ba\u7acb\u3067\u8840\u53cb\u75c5\u306b\u3001\u5973\u306e\u5b50\u306f50\uff05\u306e\u78ba\u7acb\u3067\u4fdd\u56e0\u8005\u306b\u306a\u308a\u307e\u3059\u3002\u3053\u308c\u304c\u610f\u5473\u3057\u3066\u3044\u308b\u306e\u306f\u3001<span style=\"color:#6666ff;\">\u5973\u6027\u306eX\u67d3\u8272\u4f53\u4e0a\u306e\u907a\u4f1d\u5b50\u5909\u7570\u306f\u3001\u6b63\u5e38\u306a\u76f8\u540c\u67d3\u8272\u4f53\u304c\u3042\u3063\u3066\u3082\u4fee\u5fa9\u3055\u308c\u306a\u3044<\/span>\u3068\u8a00\u3046\u3053\u3068\u3067\u3059\u3002<br \/>\n<br \/>\n\u8840\u53cb\u75c5\u4ee5\u5916\u306b\u3082\u3001\u8272\u899a\u7570\u5e38\u3084\u3001\u514d\u75ab\u7570\u5e38\u306a\u3069\u306e\u7537\u6027\u306b\u767a\u751f\u3057\u3084\u3059\u3044\u907a\u4f1d\u75c5\u306fX\u67d3\u8272\u4f53\u4e0a\u306b\u907a\u4f1d\u5b50\u5909\u7570\u304c\u3042\u308a\u3001\u8840\u53cb\u75c5\u3068\u540c\u3058\u3088\u3046\u306b\u5973\u6027\u4fdd\u56e0\u8005\u304c\u6b63\u5e38\u306a\u76f8\u540c\u67d3\u8272\u4f53\u3092\u6301\u3063\u3066\u3044\u3066\u3082\u3001\u5909\u7570\u306f\u4fee\u5fa9\u3055\u308c\u305a\u306b\u305d\u306e\u307e\u307e\u907a\u4f1d\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br \/>\n<br \/>\n<span style=\"font-size:130%;\"><span style=\"color:#009933;\">\u25cf\u76f8\u540c\u67d3\u8272\u4f53\u306b\u3088\u308b\u907a\u4f1d\u5b50\u4fee\u5fa9\u306f\u884c\u308f\u308c\u3066\u3044\u306a\u3044<\/span><\/span><br \/>\n<br \/>\n\u907a\u4f1d\u5b50\u306e\u4fee\u5fa9\u6a5f\u69cb\u3092\u8abf\u3079\u3066\u307f\u308b\u3068\u3001\u76f8\u540c\u7d44\u307f\u63db\u3048\u306b\u3088\u308b\u4fee\u5fa9\u6a5f\u69cb\u306f\u3042\u308a\u307e\u3059\u304c\u3001\u3088\u308a\u8a73\u7d30\u306b\u8abf\u3079\u3066\u307f\u308b\u3068\u3001\u76f8\u540c\u7d44\u307f\u63db\u3048\u306b\u3088\u308b\u907a\u4f1d\u5b50\u4fee\u5fa9\u306f\u3001\u76f8\u540c\u67d3\u8272\u4f53\u306b\u3088\u308b\u3082\u306e\u3067\u306f\u306a\u304f\u59c9\u59b9\u67d3\u8272\u4f53\u306b\u3088\u3063\u3066\u4fee\u5fa9\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3059\u3002<br \/>\n<br \/>\n\u59c9\u59b9\u67d3\u8272\u4f53\u3068\u306f\u3001\u81ea\u5df1\u8907\u88fd\u3057\u305f\u5206\u88c2\u524d\u306e\u30b3\u30d4\u30fc\u67d3\u8272\u4f53\u306e\u3053\u3068\u3067\u3042\u3063\u3066\u3001\u7236\u89aa\u7531\u6765\u3001\u6bcd\u89aa\u7531\u6765\u306e\u5225\u306e\u76f8\u540c\u67d3\u8272\u4f53\u3092\u6307\u3059\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002Y\u67d3\u8272\u4f53\u3082X\u67d3\u8272\u4f53\u3082\u3001\u4fee\u5fa9\u6a5f\u80fd\u306b\u306f\u5dee\u306f\u306a\u3044\u3088\u3046\u3067\u3059\u3002<br \/>\n<br \/>\n<a href=\"http:\/\/ja.wikipedia.org\/wiki\/DNA%E4%BF%AE%E5%BE%A9\">\u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2\u306e\u907a\u4f1d\u5b50\u4fee\u5fa9<\/a>\u304b\u3089\u76f8\u540c\u7d44\u307f\u63db\u3048\u306e\u8a18\u8ff0\u3092\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n<blockquote><p>\u76f8\u540c\u7d44\u63db\u3048\uff08homologous recombination: HR\uff09\u306e\u5834\u5408\u3001\u5207\u65ad\u90e8\u306e\u4fee\u5fa9\u306e\u969b\u306b\u7528\u3044\u308b\u92f3\u578b\u3068\u3057\u3066\u307e\u3063\u305f\u304f\u540c\u4e00\u304b\u3001\u3088\u304f\u4f3c\u305f\u914d\u5217\u3092\u3082\u3064\u30b2\u30ce\u30e0\u3092\u5229\u7528\u3059\u308b\u3002\u3053\u306e\u6a5f\u69cb\u306f\u7d30\u80de\u5468\u671f\u306b\u304a\u3044\u3066\u3001DNA\u306e\u8907\u88fd\u4e2d\u304b\u3001\u307e\u305f\u306f\u8907\u88fd\u7d42\u4e86\u5f8c\u306e\u9593\u306b\u304a\u3044\u3066\u4e3b\u306b\u7528\u3044\u3089\u308c\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b\u3002 \u3053\u308c\u306f<span style=\"color:#6666ff;\">\u640d\u50b7\u3092\u53d7\u3051\u305f\u67d3\u8272\u4f53\u306e\u4fee\u5fa9\u304c\u3001\u65b0\u3057\u304f\u4f5c\u6210\u3055\u308c\u305f\u76f8\u540c\u306a\u914d\u5217\u3092\u6301\u3064\u59c9\u59b9\u67d3\u8272\u5206\u4f53\u3092\u5229\u7528\u3059\u308b\u3053\u3068\u3067\u53ef\u80fd\u306b\u306a\u308b<\/span>\u304b\u3089\u3067\u3042\u308b\u3002 \u30d2\u30c8\u30b2\u30ce\u30e0\u3067\u306f\u7e70\u308a\u8fd4\u3057\u914d\u5217\u304c\u591a\u304f\u3001\u5229\u7528\u53ef\u80fd\u306a\u540c\u4e00\u306a\u914d\u5217\u3092\u591a\u304f\u542b\u3093\u3067\u3044\u308b\u3002\u3053\u308c\u3089\u306e\u4ed6\u306e\u914d\u5217\u3068\u306e\u9593\u3067\u4ea4\u5dee\u3057\u3066\u8d77\u3053\u308b\u7d44\u63db\u3048\u306b\u304a\u3044\u3066\u306f\u554f\u984c\u3092\u8d77\u3053\u3059\u3053\u3068\u304c\u591a\u304f\u3001\u7d50\u679c\u3068\u3057\u3066\u67d3\u8272\u4f53\u306e\u8ee2\u5ea7\u3084\u4ed6\u306e\u67d3\u8272\u4f53\u518d\u7de8\u6210\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u3042\u308b\u3002<\/p><\/blockquote>\n<p>\n\u59c9\u59b9\u907a\u4f1d\u5b50\u4ee5\u5916\u3068\u306e\u9593\u3067\u3082\u3001\u907a\u4f1d\u5b50\u4fee\u5fa9\u304c\u5168\u304f\u4e0d\u53ef\u80fd\u3068\u8a00\u3046\u308f\u3051\u3067\u306f\u306a\u3044\u3088\u3046\u3067\u3059\u304c\u3001\u305d\u306e\u5834\u5408\u306f\u3001\u907a\u4f1d\u5b50\u3092\u5b8c\u5168\u306b\u4fee\u5fa9\u3067\u304d\u305a\u3001\u5909\u7570\u3092\u8d77\u3053\u3059\u3053\u3068\u304c\u591a\u3044\u3088\u3046\u3067\u3059\u3002<br \/>\n<br \/>\n<span style=\"font-size:130%;\"><span style=\"color:#009933;\">\u25cfY\u67d3\u8272\u4f53\u306f\u3069\u3093\u3069\u3093\u5c0f\u3055\u304f\u306a\u3063\u3066\u304d\u3066\u3044\u308b\u3002<\/span><\/span><br \/>\n<br 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