{"id":567,"date":"2008-09-15T22:59:10","date_gmt":"2008-09-15T13:59:10","guid":{"rendered":"http:\/\/testwww.seibutsushi.net\/blog\/2008\/09\/535.html"},"modified":"2008-09-15T22:59:10","modified_gmt":"2008-09-15T13:59:10","slug":"%e3%83%8c%e3%82%af%e3%83%ac%e3%82%aa%e3%83%81%e3%83%89%e3%81%a3%e3%81%a6%e3%81%aa%e3%81%ab%ef%bc%9f","status":"publish","type":"post","link":"http:\/\/www.seibutsushi.net\/blog\/2008\/09\/567.html","title":{"rendered":"\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u3063\u3066\u306a\u306b\uff1f"},"content":{"rendered":"

\"%E7%84%A1%E9%A1%8C.JPG\"
\n\u753b\u50cf\u306f\u30b3\u30c1\u30e9<\/a>\u304b\u3089\u3002
\n\u306f\u3058\u3081\u307e\u3057\u3066MASAMUNE\u3067\u3059\u3002
\n\u4eca\u65e5\u306fDNA\u3084RNA\u3092\u8a9e\u308b\u4e0a\u3067\u91cd\u8981\u306a\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u306b\u3064\u3044\u3066\u307e\u3068\u3081\u3066\u307f\u307e\u3057\u305f\u3002
\n\u3088\u304b\u3063\u305f\u3089\u7d9a\u304d\u3092\u8aad\u3093\u3067\u307f\u3066\u304f\u3060\u3055\u3044\u3002 8)<\/p>\n

<\/p>\n

\u30cc\u30af\u30ec\u30aa\u30c1\u30c9 (nucleotide) \u3068\u306f\u3001\u30cc\u30af\u30ec\u30aa\u30b7\u30c9\u306b\u30ea\u30f3\u9178\u57fa\u304c\u7d50\u5408\u3057\u305f\u7269\u8cea\u3067\u3042\u308b\u3002\u30cc\u30af\u30ec\u30aa\u30b7\u30c9\u306f\u4e94\u5358\u7cd6\u306e1\u4f4d\u306b\u30d7\u30ea\u30f3\u5869\u57fa\u307e\u305f\u306f\u30d4\u30ea\u30df\u30b8\u30f3\u5869\u57fa\u304c\u30b0\u30ea\u30b3\u30b7\u30c9\u7d50\u5408\u3057\u305f\u3082\u306e\u3002DNA\u3084RNA\u3092\u69cb\u6210\u3059\u308b\u5358\u4f4d\u3067\u3082\u3042\u308b\u3002
\n\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u53ca\u3073\u305d\u306e\u7d50\u5408\u4f53\u3067\u3042\u308b\u30dd\u30ea\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u3001DNA\u3001RNA\u306f\u751f\u7269\u3092\u539f\u6599\u3068\u3059\u308b\u307b\u3068\u3093\u3069\u306e\u98df\u54c1\u306b\u5fae\u91cf\u542b\u307e\u308c\u3066\u3044\u308b\u3002\u3053\u308c\u3092\u6442\u53d6\u3059\u308b\u3068\u3001\u4f53\u5185\u3067RNA\u3001DNA\u3092\u52b9\u7387\u7684\u306b\u5408\u6210\u3059\u308b\u6750\u6599\u3068\u306a\u308b\u3002
\n\u30b0\u30a2\u30cb\u30eb\u9178 (GMP) \u3084\u30a4\u30ce\u30b7\u30f3\u9178 (IMP) \u306f\u5448\u5473\u6027\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u3068\u547c\u3070\u308c\u3001\u81ea\u8eab\u304c\u3046\u307e\u5473\u3092\u3082\u3064\u307b\u304b\u3001L-\u30b0\u30eb\u30bf\u30df\u30f3\u9178\u30ca\u30c8\u30ea\u30a6\u30e0\u3068\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001\u3046\u307e\u5473\u304c\u5f37\u307e\u308b\u52b9\u679c\u304c\u3042\u308a\u3001\u3046\u307e\u5473\u8abf\u5473\u6599\u3084\u3001\u30b9\u30fc\u30d7\u539f\u6599\u306a\u3069\u3068\u3057\u3066\u4f7f\u7528\u3055\u308c\u3066\u3044\u308b\u3002\uff08Wikipedia<\/a>\uff09<\/p><\/blockquote>\n

\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u306fDNA\uff08\u30c7\u30aa\u30ad\u30b7\u30ea\u30dc\u6838\u9178\uff09\u3084RNA\uff08\u30ea\u30dc\u6838\u9178\uff09\u3068\u3044\u3063\u305f\u6838\u9178\u3092\u4f5c\u308b\u306e\u306b\u5fc5\u8981\u306a\u6210\u5206\u3067\u3059\u3002\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u3092\u5408\u6210\u3057\u3066\u751f\u7269\u306fDNA\u3084RNA\u3092\u4f5c\u3063\u3066\u3044\u307e\u3059\u3002
\n\u305d\u3082\u305d\u3082DNA\u3084RNA\u3063\u3066\u306a\u306b\uff1f\u3063\u3066\u65b9\u306f\u4e0b\u306e\u8a18\u4e8b\u3092\u304a\u8aad\u307f\u304f\u3060\u3055\u3044\u3002
\n7\/27\u306a\u3093\u3067\u3084\u5287\u5834\u30ec\u30dd\u30fc\u30c8\uff11\uff5e\u751f\u547d\u306e\u57fa\u5e79\u30b7\u30b9\u30c6\u30e0\u3092\u63a2\u308b\uff5e<\/a>
\n7\/27\u306a\u3093\u3067\u3084\u5287\u5834\u30ec\u30dd\u30fc\u30c8\uff12\uff5e\u751f\u547d\u306e\u57fa\u5e79\u30b7\u30b9\u30c6\u30e0\u3092\u63a2\u308b\uff5e<\/a>
\n\u7c21\u5358\u306b\u8a00\u3048\u3070\u3001DNA\u306f\u751f\u7269\u306e\u8a2d\u8a08\u56f3\u3001RNA\u306f\u4f53\u306b\u5fc5\u8981\u306a\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u5408\u6210\u3057\u3066\u304f\u308c\u308b\u3082\u306e\u3067\u3059\u3002
\n\u4e21\u65b9\u3068\u3082\u751f\u7269\u306b\u3068\u3063\u3066\u8d85\u91cd\u8981\uff01\u305d\u308c\u3092\u69cb\u6210\u3059\u308b\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u3082\u8d85\u91cd\u8981\uff01\u3060\u304b\u3089\u98df\u3079\u308b\u3068\u304a\u3044\u3057\u304f\u611f\u3058\u308b\u306e\u3060\u3068\u601d\u3044\u307e\u3059 \ud83d\ude00 \u3002
\n\u3061\u306a\u307f\u306b\u3000\u300c\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\uff1d \u5869\u57fa\uff0b \u7cd6\uff0b \u30ea\u30f3\u9178\u300d\u3000\u7cd6\u304c\u5165\u3063\u3066\u3044\u308b\u3053\u3068\u304b\u3089\u3082\u304a\u3044\u3057\u304f\u611f\u3058\u308b\u3068\u3044\u3046\u3068\u3053\u308d\u306f\u308f\u304b\u308a\u307e\u3059\u3088\u306d\u3002
\n\u3055\u3066\u3001\u98df\u3079\u305f\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u306f\u751f\u7269\u306e\u4f53\u5185\u3067\u5408\u6210\u3055\u308c\u307e\u3059\u3002\u5408\u6210\u306e\u65b9\u6cd5\u306f\uff12\u3064\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306f\u5168\u3066\u306e\u751f\u7269\u3067\u5171\u901a\u306e\u65b9\u6cd5\u3067\u3059 \u3002
\n1.de novo\u5408\u6210
\n\u3000de novo \u5408\u6210\u3068\u306f\u3001\u30e9\u30c6\u30f3\u8a9e\u306e\u201c\u65b0\u898f\u306e\u201d\u304c\u8a9e\u6e90\u3001\u4ee5\u524d\u306f\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u306e\u4e00\u3064\u306e\u3000\u5408\u6210\u7cfb\u3092\u6307\u3059\u72ed\u3044\u610f\u5473\u306b\u4f7f\u308f\u308c\u3066\u3044\u305f\u304c\u3001\u73fe\u5728\u3067\u306f\u751f\u4f53\u69cb\u6210\u6210\u5206\u304c\u3001\u7c21\u5358\u306a\u7d20\u6750\u3000\u304b\u3089\u65b0\u305f\u306b\u5408\u6210\u3055\u308c\u308b\u3053\u3068\u3092\u793a\u3059\u7528\u8a9e\u3067\u3042\u308b\u3002
\n\u3000\u98df\u3079\u305f\u3082\u306e\u304b\u3089\u65b0\u3057\u304f\u5408\u6210\u3059\u308b\u65b9\u6cd5\u304c\u3053\u308c\u306b\u3042\u305f\u308a\u307e\u3059 \ud83d\ude00 \u3002
\n2.salvage\u5408\u6210\u3000
\n\u3000salvage \u5408\u6210\u3068\u306f\u3001\u5ec3\u7269\u5229\u7528\u3068\u3044\u3046\u8a9e\u6e90\u304b\u3089\u304d\u305f\u3082\u306e\u3067\u3001\u305d\u306e\u7269\u8cea\u306e\u4ee3\u8b1d\u4e2d\u9593\u4f53\u3001 \u7279\u306b\u90e8\u5206\u5206\u89e3\u7523\u7269\u3092\u7d20\u6750\u3068\u3057\u3066\u3001\u305d\u306e\u7269\u8cea\u304c\u518d\u5408\u6210\u3055\u308c\u308b\u3053\u3068\u3092\u8a00\u3046\u3002\u3000
\n\u3000\u4f7f\u7528\u6e08\u307f\u306b\u306a\u3063\u305f\u6838\u9178\uff08DNA\u3084RNA\uff09\u306e\u5927\u534a\u306f\u6392\u6cc4\u3059\u308b\u306e\u3067\u3059\u304c\u3001\u4e00\u90e8\u306f\u518d\u5229\u7528\u3055\u308c\u307e\u3059\u3002\u305d\u306e\u518d\u5229\u7528\u3055\u308c\u305f\u5834\u5408\u306e\u5408\u6210\u6cd5\u304c\u3053\u308c\u306b\u3042\u305f\u308a\u307e\u3059 \ud83d\ude44 \u3002
\n\u3061\u306a\u307f\u306b\u5272\u5408\u3068\u3057\u3066\u306f\u3001de novo\u5408\u6210\u304c\u307b\u3068\u3093\u3069\u3067\u3059\u3002
\n\u53c2\u8003\uff1a\u30ea\u30f3\u30af<\/a>
\n\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u306b\u306f\u5927\u304d\u304f\uff12\u7a2e\u985e\u3042\u3063\u3066\u30d7\u30ea\u30f3\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u3068\u30d4\u30ea\u30df\u30b8\u30f3\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u304c\u3042\u308a\u307e\u3059\u3002\u5f53\u7136\uff12\u3064\u3068\u3082\u5408\u6210\u904e\u7a0b\u306f\uff12\u901a\u308a\u3042\u308a\u307e\u3059\u3002
\n\u53c2\u8003\uff1a\u30ea\u30f3\u30af<\/a>
\n\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u306f\u3069\u3053\u3067\u5408\u6210\u3055\u308c\u308b\u306e\uff1f
\n\u7cd6\u9396\u5408\u6210\u306e\u57fa\u8cea\u3067\u3042\u308b\u7cd6\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u306f\u7d30\u80de\u8cea\u4e2d\u3067\uff08CMP-sialic acid\u3060\u3051\u306f\u6838\u3067\uff09\u5408\u6210\u3055\u308c\u308b\u819c\u4e0d\u900f\u904e\u6027\u306e\u7269\u8cea\u3067\u3042\u308b\u3002
\n\u53c2\u8003\uff1a\u30ea\u30f3\u30af<\/a>
\n\u305f\u3060\u3057\u3001\u3053\u3053\u306e\u8a18\u8ff0\u306b\u3042\u308b\u7cd6\u9396\u3068\u6838\u9178\u306f\u9055\u3046\u3082\u306e\u3067\u3059\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u3053\u3053\u306e\u4f8b\u306b\u6319\u3052\u3089\u308c\u3066\u3044\u308bCMP\uff08\u30d4\u30ea\u30df\u30b8\u30f3\u5869\u57fa\u3092\u3064\u304f\u308b\u305f\u3081\u306b\u5fc5\u8981\u306a\u30b7\u30a2\u30eb\u9178\uff09\u306f\u30d4\u30ea\u30df\u30b8\u30f3\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u3092\u69cb\u6210\u3059\u308b\u5869\u57fa\u3067\u3082\u3042\u308b\u305f\u3081\u3001\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u306f\u7d30\u80de\u8cea\uff08\uff1d\u7d30\u80de\u306e\u4e2d\u3067\u6838\u4ee5\u5916\uff08\u7d30\u80de\u819c\u3092\u542b\u3080\uff09\uff09\u3067\u3057\u304b\u4f5c\u308c\u306a\u3044\u3068\u3044\u3048\u308b\u3067\u3057\u3087\u3046\u3002
\n\u3053\u308c\u3089\u3092\u3075\u307e\u3048\u3066\u5177\u4f53\u7684\u306b\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u304c\u3069\u306e\u3088\u3046\u306b\u3067\u304d\u3066\u3044\u304f\u304b\u3092\u8003\u3048\u3066\u307f\u308b\u3068\u3001\u7269\u3092\u98df\u3079\u3066\u5f97\u305f\u990a\u5206\uff08\u5869\u57fa\u3084\u7cd6\u3084\u30ea\u30f3\u9178etc.\uff09\u3092\u8840\u6db2\u3067\u4f53\u5185\u306e\u7d30\u80de\u306b\u5206\u914d\u3057\u3001\u7d30\u80de\u5185\u3067\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u3092\u751f\u6210\u3057\u3066\u3044\u308b\u3068\u3044\u3048\u307e\u3059\u3002
\n\u3061\u306a\u307f\u306b\u7d30\u80de\u5468\u671f\u306b\u3088\u308a\u7d30\u80de\u5185\u306e\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u6fc3\u5ea6\u306f\u5909\u5316\u3059\u308b\u3088\u3046\u3067\u3059 \u3002
\n\uff24\uff2e\uff21\u8907\u88fd\u304c\u884c\u308f\u308c\u308b\u7d30\u80de\u5468\u671f\u306e\uff33\u671f\uff08\u5408\u6210\u671f\uff09\u306b\u306e\u307f\u3001\u30c7\u30aa\u30ad\u30b7\u30ea\u30dc\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u306e\u7d30\u80de\u5185\u6fc3\u5ea6\u306f\u4e0a\u6607\u3057\u3001\u305d\u308c\u3092\u5408\u6210\u3059\u308b\u8af8\u9175\u7d20\u3082\uff33\u671f\u306b\u4e0a\u6607\u3057\u307e\u3059\u3002
\n\u53c2\u8003\uff1a\u30ea\u30f3\u30af<\/a>
\n\u4ee5\u4e0a\u57fa\u790e\u7de8\u3067\u3057\u305f\u3002\u6b21\u56de\u306f\u3082\u3046\u5c11\u3057\u6398\u308a\u4e0b\u3052\u3066\u8003\u3048\u3066\u3044\u304d\u307e\u3059 \ud83d\ude00 \u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u753b\u50cf\u306f\u30b3\u30c1\u30e9\u304b\u3089\u3002 \u306f\u3058\u3081\u307e\u3057\u3066MASAMUNE\u3067\u3059\u3002 \u4eca\u65e5\u306fDNA\u3084RNA\u3092\u8a9e\u308b\u4e0a\u3067\u91cd\u8981\u306a\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u306b\u3064\u3044\u3066\u307e\u3068\u3081\u3066\u307f\u307e\u3057\u305f\u3002 \u3088\u304b\u3063\u305f\u3089\u7d9a\u304d\u3092\u8aad\u3093\u3067\u307f\u3066\u304f\u3060\u3055\u3044\u3002 8)<\/p>\n","protected":false},"author":54,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_mi_skip_tracking":false},"categories":[],"tags":[],"aioseo_notices":[],"_links":{"self":[{"href":"http:\/\/www.seibutsushi.net\/blog\/wp-json\/wp\/v2\/posts\/567"}],"collection":[{"href":"http:\/\/www.seibutsushi.net\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.seibutsushi.net\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.seibutsushi.net\/blog\/wp-json\/wp\/v2\/users\/54"}],"replies":[{"embeddable":true,"href":"http:\/\/www.seibutsushi.net\/blog\/wp-json\/wp\/v2\/comments?post=567"}],"version-history":[{"count":0,"href":"http:\/\/www.seibutsushi.net\/blog\/wp-json\/wp\/v2\/posts\/567\/revisions"}],"wp:attachment":[{"href":"http:\/\/www.seibutsushi.net\/blog\/wp-json\/wp\/v2\/media?parent=567"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.seibutsushi.net\/blog\/wp-json\/wp\/v2\/categories?post=567"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.seibutsushi.net\/blog\/wp-json\/wp\/v2\/tags?post=567"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}